Study of reticuloendothelial phagocytic capacity in patients with cholestasis.

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Study of reticuloendothelial phagocytic capacity in patients with cholestasis.

The phagocytic capacity of the reticuloendothelial system was studied by the clearance from the plasma of microaggregated iodinated human serum albumin. About half of the patients with cholestasis showed impaired Kupffer-cell phagocytosis. The finding may be relevant to the occurrence of surgical complications in patients with obstructive jaundice.

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Studies of the reticuloendothelial system (RES). II. Changes in the phagocytic capacity of the RES in patients with certain infections.

In our previous communication (1), we have presented data indicating that the phagocytic capacity of the reticuloendothelial system (RES) can be determined by measuring the rate of disappearance of various doses of radioisotopically labeled aggregated albumin particles from the circulation. Since our results followed the mathematical model suggested first by Michaelis and Menten in their studie...

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ژورنال

عنوان ژورنال: BMJ

سال: 1976

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.6025.1568